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Neurogenic Bowel Dysfunction treatment assessment

Bowel Dysfunction (NBD) affects up to 80 % of the spinal cord injury (SCI) population. The validated NBD Score allows assessment of the severity of bowel symptoms and correlates with impaired quality of life but does not address clinical decision making in individual patients presenting with an ineffective bowel regimen. Therefore, Monitoring Efficacy of NBD Treatment On Response (MENTOR) was developed by a group of international experts in the field of NBD as a standardised way to quickly and accurately assess the effectiveness of NBD treatment regimen in SCI patients.

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Clinical Evidence of Peristeen® in Low Anterior Resection Syndrome (LARS)

Colorectal cancer is the second and third most common type of cancer in women and men. Surgical resection is often indicated, and anterior resection techniques may allow patients to keep their anal sphincter. However, functional problems arising after surgery lead to a constellation of symptoms defined as low anterior resection syndrome (LARS) in up to 80% of patients. Symptoms of LARS include faecal incontinence or urgency, frequent or fragmented bowel movements, emptying difficulties, and increased intestinal gas.

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A Randomized, Controlled Trial of Transanal Irrigation Versus Conservative Bowel Management in Spinal Cord–Injured Patients

Bowel dysfunction in patients with spinal cord injury often causes constipation, fecal incontinence, or a combination of both with a documented impact on quality of life. The aim of the study was to compare transanal irrigation (TAI) (Peristeen®, Coloplast) with conservative bowel management (best supportive bowel care without irrigation).

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Clinical Evidence of Peristeen® for the Treatment of Neurogenic Bowel Dysfunction in Multiple Sclerosis

Multiple sclerosis (MS) is an immune-mediated inflammatory and progressive central neurologic disease, affecting both brain and spinal cord, but also causing bowel disturbance (most often chronic constipation (CC) and fecal incontinence (FI)), known as neurogenic bowel dysfunction (NBD) in over two-thirds of patients.

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Clinical evidence of Peristeen® in reducing urinary tract infections in neurogenic bowel dysfunction

Chronic constipation (CC) is a plausible contributor to the development of urinary tract infections (UTIs) in some patients, due to distending rectal pressure (often in the case of faecal impaction) on the bladder wall, which causes obstruction of urine flow and bladder detrusor function impairment.

Management guidelines for low anterior resection syndrome – the MANUEL project

Eight colorectal surgeons and gastroenterologists with expertise in the assessment and management of low anterior resection syndrome (LARS) aimed to develop a practical guidance for healthcare professionals who manage LARS patients. The MANUEL project is an up-to-date consensus summary covering all aspects of LARS pathophysiology, assessment, and management.


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Predictive factors for compliance with transanal irrigation

This retrospective analysis evaluated 108 patients who used transanal irrigation over a 4-year period.  Compliance with Peristeen transanal irrigation and predictive factors for compliance were evaluated.


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